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Pharmacists should consider dispensing with a child-resistant closure and advise patients to store colchicine out of sight and reach of children If the patient is taking very-low-dose colchicine for flare prophylaxis, this must be stopped during low-dose colchicine treatment for an acute flare, i.e

Use sterile needles, and never place them on a surface before use

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Most clinical evidence comes from case reports and clinical observations, not large-scale controlled trials It is important to maintain realistic expectations and recognize that animal research does not always translate directly to human outcomes

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